Bioactivity | GS-6620 is?potent and selective pangenotype HCV inhibitor against HCV replicons of genotypes 1 to 6 (EC50: 0.048 to 0.68 μM). GS-6620 shows limited activities against other viruses, maintaining only some of its activity against the closely related bovine viral diarrhea virus (EC50, 1.5 μM)[1]. |
Target | IC50: 48-680 nM (HCV replicons of genotypes 1 to 6) |
Name | GS-6620 |
CAS | 1350735-70-4 |
Formula | C29H37N6O9P |
Molar Mass | 644.61 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Joy Y Feng, et al. Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug. Antimicrob Agents Chemother. 2014;58(4):1930-42. |