PeptideDB

GRP75-IN-1 hydrochloride

CAS: F: C27H39ClN4OS W: 503.14

GRP75-IN-1 hydrochloride (compound 33) is an anti-endometrial cancer (EC) agent that induces apoptosis. GRP75-IN-1 hydro
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity GRP75-IN-1 hydrochloride (compound 33) is an anti-endometrial cancer (EC) agent that induces apoptosis. GRP75-IN-1 hydrochloride reduces Ca2+ levels in mitochondria by targeting GRP75 and disrupting its interaction with IP3R[1].
Formula C27H39ClN4OS
Molar Mass 503.14
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ling X, et al. Discovery of Novel Azaphenothiazine Derivatives to Suppress Endometrial Cancer by Targeting GRP75 to Impair Its Interaction with IP3R and Mitochondrial Ca2+ Homeostasis. J Med Chem. 2024 Jul 31.