| Bioactivity | GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra[1][2]. |
| Invitro | GR 87389 是一种非肽和肽速激肽拮抗剂，对海马、膀胱和十二指肠的 Ki 值分别为 4.0、5.2 和 14 nM[1]。GR 87389 (30-300 nM) 拮抗 GA 64349 诱导的人类逼尿肌、前列腺和前列腺尿道平滑肌条收缩[2]。 |
| Name | GR 87389 |
| CAS | 141663-86-7 |
| Shortening | {Boc}-AA-{D-Trp}-F-{D-Pro}-P-{Nle}-NH2 |
| Formula | C47H65N9O9 |
| Molar Mass | 900.07 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |