GPX4-IN-6_product_DataBase

CAS: 2922824-07-3 F: C18H17BrFNO5 W: 426.23

GPX4-IN-6 (Compound C25) is a GPX4 covalent inhibitor with an IC50 value of 0.13 μM.GPX4-IN-6 (Compound C25) can induce

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	GPX4-IN-6 (Compound C25) is a GPX4 covalent inhibitor with an IC50 value of 0.13 μM. GPX4-IN-6 (Compound C25) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].
Target	IC50: 0.13 μM (GPX4)
Name	GPX4-IN-6
CAS	2922824-07-3
Formula	C18H17BrFNO5
Molar Mass	426.23
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

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