| Bioactivity | GPX4-IN-16 ((R)-9i) is a potent GPX4 inhibitor with an KD value of 20.4 nM. GPX4-IN-16 shows cytotoxicity. GPX4-IN-16 shows anticancer activity[1]. |
| Target | KD: 20.4 nM (GPX4) |
| Formula | C29H24N4O3S2 |
| Molar Mass | 540.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gu S, et al. Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2-Ethynylthiazole-4-carboxamide as Electrophilic Warhead. J Med Chem. 2025 Jan 30. |