| Bioactivity | GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1]. |
| Name | GPVI antagonist 3 |
| CAS | 901654-94-2 |
| Formula | C22H23N3O4 |
| Molar Mass | 393.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Olğaç S, et al. Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study. Bioorg Chem. 2022;121:105661. |
GPVI antagonist 3
CAS: 901654-94-2 F: C22H23N3O4 W: 393.44
GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are
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