Bioactivity | GPSVFPLAPSSK-13C6,15N2 TFA is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies[1][2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> GPSVFPLAPSSK-13C6,15N2 TFA 相关抗体: |
Sequence | Gly-Pro-Ser-Val-Phe-Pro-Leu-Ala-Pro-Ser-Ser-{Lys-13C6,15N2} |
Shortening | GPSVFPLAPSS-{Lys-13C6,15N2} |
Formula | C4913C6H87N1115N2O16.xC2HF3O2 |
Molar Mass | 1194.30 (free base) |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. de Jong KAM, et al. Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS. J Pharm Biomed Anal. 2021 Oct 25;205:114319. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-226. |