Bioactivity | GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1]. |
Target | EC50: 1.4 μM (GPR35).Ki: 0.0508 μM (GPR35).IC50: 0.349 μM (GPR35). |
Invitro | GPR35 agonist 3 shows GPR35 agonist potency with an EC50 value of 1.4 μM[1].GPR35 agonist 3 has affinity and potency for GPR35 with values of 0.0508μM (Ki) and 0.349 μM (IC50)[1]. |
Name | GPR35 agonist 3 |
CAS | 123021-85-2 |
Formula | C12H9NO5S |
Molar Mass | 279.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Dominik Thimm, et al. 6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem |