| Bioactivity | GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT)[1][2][3]. | ||||||
| Invitro | GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization[3]. | ||||||
| Name | GPLGIAGQ TFA | ||||||
| Sequence | Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln | ||||||
| Shortening | GPLGIAGQ | ||||||
| Formula | C33H54F3N9O12 | ||||||
| Molar Mass | 825.83 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |