| Bioactivity | GNE-293 is a potent and selective PI3Kδ inhibitor (IC50 = 4.38 nM). GNE-293 has favorable pharmacokinetic properties. GNE-293 can be used for research of asthma, rheumatoid arthritis, and other inflammatory disorders[1]. |
| Target | 4.38 nM (PI3Kδ). |
| Name | GNE-293 |
| CAS | 1354955-67-1 |
| Formula | C28H36N8O4S |
| Molar Mass | 580.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Safina BS, et al. Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4953-9. |