| Bioactivity | GLS1 Inhibitor-6 (Compound 24y) is an orally active, potent and selective glutaminase 1 (GLS1) inhibitor (IC50=68 nM), shows 220-fold selectivity for GLS2. GLS1 Inhibitor-6 shows good anti-tumor activity, antitumor cell proliferation activity and induces apoptosis[1]. |
| Invitro | GLS1 Inhibitor-6 (0-10 μM) inhibts cancer cell growth[1].GLS1 Inhibitor-6 (1-10 μM, 48 h) can induce A549 cell apoptosis[1].GLS1 Inhibitor-6 (50-800 nM, 48 h) can induce cell cycle arrest in the G1 phase[1]. Cell Viability Assay[1] Cell Line: |
| Name | GLS1 Inhibitor-6 |
| Formula | C37H52N6O3S |
| Molar Mass | 660.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |