GLP-2(3-33) (Leu-13C6,15N)_product_DataBase

Bioactivity	GLP-2(3-33) (Leu-13C6,15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
Invitro	氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 0 --> GLP-2(3-33) (Leu-13C6,15N) 相关抗体:
Name	GLP-2(3-33) (Leu-13C6,15N)
Sequence	Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-{Leu-13C6,15N}-Ile-Gln-Thr-Lys-Ile-Thr-Asp
Shortening	DGSFSDEMNTI-{Leu-13C6,15N}-DNLAARDFINWLIQTKITD
Formula	C15013C6H242N3915NO53S
Molar Mass	3564.84
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

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