| Bioactivity | GL-331 is a potent anti-cancer agent. GL-331 has demonstrated more efficacious anti-cancer activity in both the in vitro and in vivo lymphoma systems[1]. |
| Invitro | GL-331 在杀死癌细胞方面比 VP-16 (HY-13629) 更有效。即使在 MDR-1 过表达细胞系（如 HCC36 和 SW620）中，GL-331 也具有更强的细胞杀伤活性。其更高的细胞毒性可以归因于诱导细胞凋亡的能力增强[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> GL-331 相关抗体: |
| CAS | 127882-73-9 |
| Formula | C27H24N2O9 |
| Molar Mass | 520.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. [2]. Huang TS, et al. A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells. Pharm Res. 1999 Jul;16(7):997-1002. |