| Bioactivity | GK187 is a potent and selective Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor with an XI(50) value of 0.0001. GK187 can be used for researching various neurological disorders[1].[The XI(50) is the mole fraction of the inhibitor in the total substrate interface required to inhibit the enzyme by 50%.] | ||||||||||||
| Target | XI(50): 0.0001 (GVIA iPLA2) | ||||||||||||
| Name | GK187 | ||||||||||||
| CAS | 1071001-50-7 | ||||||||||||
| Formula | C14H15F5O2 | ||||||||||||
| Molar Mass | 310.26 | ||||||||||||
| Appearance | Liquid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Magrioti V, et al. New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2. Bioorg Med Chem. 2013 Sep 15;21(18):5823-9. |