| Bioactivity | GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymerase, interupts the viral RNA synthesis, and inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with EC50 of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models[1]. |
| CAS | 1269267-87-9 |
| Formula | C16H11FN2O |
| Molar Mass | 266.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cox RM, et al., Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase. Nat Microbiol. 2020 Oct;5(10):1232-1246. |
GHP-88309
CAS: 1269267-87-9 F: C16H11FN2O W: 266.27
GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymeras
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