| Bioactivity | GGDPS-IN-1 (Compound 37) is a geranylgeranyl diphosphate synthase (GGDPS) inhibitor with an IC50 of 49.4 nM. GGDPS-IN-1 disrupts protein geranylgeranylation in myeloma cells[1]. |
| Target | Geranylgeranyl Diphosphate Synthase (GGDPS) |
| Formula | C15H28N4O6P2 |
| Molar Mass | 422.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gehrke NR, et al. α-Amino bisphosphonate triazoles serve as GGDPS inhibitors. Bioorg Med Chem Lett. 2024 Feb 17:129659. |