PeptideDB

GFRα2/3-IN-1

CAS: F: C36H39N5O3 W: 589.73

GFRα2/3-IN-1 (Compound 16) is a selective GFRα2/3 inhibitor with IC50 values of 0.1 and 0.2 μM for GFRα2 and GFRα3,
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity GFRα2/3-IN-1 (Compound 16) is a selective GFRα2/3 inhibitor with IC50 values of 0.1 and 0.2 μM for GFRα2 and GFRα3, respectively. GFRα2/3-IN-1 can be used to study pain and itch[1].
Formula C36H39N5O3
Molar Mass 589.73
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Johnson SL, et al. Discovery of the first selective, small-molecule GFRα2/3 inhibitors through DNA-encoded library technology. Bioorg Med Chem Lett. 2024 Sep 15;110:129889.