Bioactivity | GFRα2/3-IN-1 (Compound 16) is a selective GFRα2/3 inhibitor with IC50 values of 0.1 and 0.2 μM for GFRα2 and GFRα3, respectively. GFRα2/3-IN-1 can be used to study pain and itch[1]. |
Formula | C36H39N5O3 |
Molar Mass | 589.73 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Johnson SL, et al. Discovery of the first selective, small-molecule GFRα2/3 inhibitors through DNA-encoded library technology. Bioorg Med Chem Lett. 2024 Sep 15;110:129889. |