| Bioactivity | GD3 Ganglioside sodium is a prominent ganglioside of human melanoma. GD3 Ganglioside sodium is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis[1]. |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rippo MR, et al. GD3 ganglioside directly targets mitochondria in a bcl-2-controlledfashion. FASEB J. 2000 Oct;14(13):2047-54. |