| Bioactivity | G6PI 325-339 (human) is an efficient inducer of arthritis in B10.Q mice. G6PI 325-339 (human) primes Th1 and Th17 cells cross-reacted with the murine G6PI protein. G6PI 325-339 (human) induces arthritis model operating through a T and B cell-dependent pathway but without antibody effector mechanisms[1]. |
| Name | G6PI 325-339 (human) |
| CAS | 1174631-35-6 |
| Sequence | Ile-Trp-Tyr-Ile-Asn-Cys-Phe-Gly-Cys-Glu-Thr-His-Ala-Met-Leu |
| Shortening | IWYINCFGCETHAML |
| Formula | C82H117N19O21S3 |
| Molar Mass | 1801.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Angela Pizzolla, et al. A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement. Am J Pathol. 2013 Oct;183(4):1144-1155. |
G6PI 325-339 (human)
CAS: 1174631-35-6 F: C82H117N19O21S3 W: 1801.12
G6PI 325-339 (human) is an efficient inducer of arthritis in B10.Q mice. G6PI 325-339 (human) primes Th1 and Th17 cells
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