Bioactivity | G-Protein antagonist peptide TFA is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide TFA inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[1]. | ||||||
Name | G-Protein antagonist peptide TFA | ||||||
Sequence | {Glp}-Gln-Trp-Phe-Trp-Trp-Met-NH2 | ||||||
Shortening | {Glp}QWFWWM-NH2 | ||||||
Formula | C59H65F3N12O11S | ||||||
Molar Mass | 1207.28 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |