| Bioactivity | Fumonisin B2-13C34 is the 13C labeled Fumonisin B2 (HY-N6723)[1]. Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis[2][3]. |
| Target | Sphingosine N-acyltransferase |
| Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 |
| Name | Fumonisin B2-13C34 |
| CAS | 1217481-36-1 |
| Formula | 13C34H59NO14 |
| Molar Mass | 739.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. |
Fumonisin B2-13C34
CAS: 1217481-36-1 F: 13C34H59NO14 W: 739.58
Fumonisin B2-13C34 is the 13C labeled Fumonisin B2 (HY-N6723). Fumonisin B2, a mycotoxin produced by Fusarium moniliform
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