| Bioactivity | Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[1][2]. |
| Invitro | Fumonisin B1 alters the gene expression and signal transduction pathways in monkey kidney cells[3].Fumonisin B1 increases the initial disruption of sphingolipid metabolism and the accumulation of sphinganine in LLC-PK1 kidney cells, causes DNA damage of apoptotic type in rat astrocytes[3]. |
| Name | Fumonisin B1 |
| CAS | 116355-83-0 |
| Formula | C34H59NO15 |
| Molar Mass | 721.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Fumonisin B1
CAS: 116355-83-0 F: C34H59NO15 W: 721.83
Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyl
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