Bioactivity | Fotagliptin is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM). Fotagliptin displays great security in rat and dog. Fotagliptin can be used for Type 2 diabetes mellitus research[1]. |
In Vivo | Fotagliptin (33 mg/kg 或 110 mg/kg) 在不同剂量下对大鼠和狗是安全的[1]。 |
Name | Fotagliptin |
CAS | 1312954-58-7 |
Formula | C17H19FN6O |
Molar Mass | 342.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang Z, et al. Development and validation of a UPLC-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine. Bioanalysis. 2017 Feb;9(4):381-393. |