Fortunellin_product_DataBase

Bioactivity	Fortunellin, is a flavonoid, that can be isolated from the fruits of Fortunella margarita (kumquat). Fortunellin exhibits little toxicity to mice and suppresses inflammation and ROS generation in H9C2 cells induced by LPS. Fortunellin protects against fructose-induced inflammation and oxidative stress by enhancing AMPK/Nrf2 pathway. Fortunellin can be used for diabetic cardiomyopathy research[1].
Invitro	Fortunellin 促进 AMPK 磷酸化，诱导 Nrf2 信号传导，通过上调 SOD、CAT 和 HO-1 作为抗氧化因子，从而显着减少氧化应激[2]。 0 --> Fortunellin 相关抗体:
Name	Fortunellin
CAS	20633-93-6
Formula	C28H32O14
Molar Mass	592.55
Appearance	固体
Transport	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Zhao C, et al. Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation. Biochem Biophys Res Commun. 2017 Aug 19;490(2):552-559. [2]. Entezari M, et al. AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation. Biomed Pharmacother. 2022 Feb;146:112563.

PeptideDB