Bioactivity | Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury[1][2][3]. |
In Vivo | Formoterol hemifumarate hydrate (0.3 mg/kg; IP; TBI-injured C57BL/6 male mice) induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury (TBI)[3]. |
Name | Formoterol hemifumarate hydrate |
CAS | 183814-30-4 |
Formula | C19H24N2O4.1/2C4H4O4.H2O |
Molar Mass | 840.91 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bartow RA, et al. An update of its pharmacological properties and therapeutic efficacy in the management of asthma [published correction appears in Drugs 1998 Apr;55(4):517]. Drugs. 1998;55(2):303-322. [2]. Tashkin DP. Formoterol for the Treatment of Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2020;15:3105-3122. Published 2020 Nov 27. [3]. Vekaria HJ, et al. Formoterol, a β2-adrenoreceptor agonist, induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury. Neurobiol Dis. 2020;140:104866. |