| Bioactivity | Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. |
| Invitro | Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Fodipir (Dp-dp; Dipyridoxyl diphosphate; 100 μM) shows the best cytopretective effect on 7β-OH-mediated cell death after treatment for 8 h. Fodipir also reduces 7β-OH-induced cellular ROS production and lysosomal membrane permeabilization (LMP)[1]. |
| Name | Fodipir |
| CAS | 118248-91-2 |
| Formula | C22H32N4O14P2 |
| Molar Mass | 638.46 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
| Reference | [1]. Laskar A, et al. Fodipir and its dephosphorylated derivative dipyridoxyl ethyldiamine are involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Pharmacology. 2013;92(3-4):182-6. |
Fodipir
CAS: 118248-91-2 F: C22H32N4O14P2 W: 638.46
Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycho
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