| Bioactivity | Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | ||||||||||||
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. | ||||||||||||
| Name | Fmoc-NH-PEG8-CH2CH2COOH | ||||||||||||
| CAS | 756526-02-0 | ||||||||||||
| Formula | C34H49NO12 | ||||||||||||
| Molar Mass | 663.75 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Fmoc-NH-PEG8-CH2CH2COOH
CAS: 756526-02-0 F: C34H49NO12 W: 663.75
Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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