Bioactivity | Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
Name | Fmoc-Gly3-Val-Cit-PAB |
CAS | 2647914-09-6 |
Formula | C39H48N8O9 |
Molar Mass | 772.85 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Reference | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |