| Bioactivity | Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1]. | ||||||
| Invitro | Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1]. | ||||||
| Name | Fmoc-Ala-Glu-Asn-Lys-NH2 | ||||||
| CAS | 220701-06-4 | ||||||
| Shortening | {Fmoc}-AENK-NH2 | ||||||
| Formula | C33H43N7O9 | ||||||
| Molar Mass | 681.74 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
Fmoc-Ala-Glu-Asn-Lys-NH2
CAS: 220701-06-4 F: C33H43N7O9 W: 681.74
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precurso
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