| Bioactivity | Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3]. | ||||||||||||
| Invitro | Flurbiprofen (2-20 nM; 12-48 hours) significantly decreases SW620 cells proliferation in a concentration- and time-dependent manner[1].Flurbiprofen (10 nM; 24 hours) decreases COX-2 expression[1].Flurbiprofen (10 nM; 24 hours) inhibits the expression of inflammatory factors by inhibiting COX-2[1].Flurbiprofen (10 nM; 24 hours) promotes the apoptosis of colorectal cancer cells by inhibiting COX-2[1]. Cell Proliferation Assay[1] Cell Line: | ||||||||||||
| Name | Flurbiprofen | ||||||||||||
| CAS | 5104-49-4 | ||||||||||||
| Formula | C15H13FO2 | ||||||||||||
| Molar Mass | 244.26 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Flurbiprofen
CAS: 5104-49-4 F: C15H13FO2 W: 244.26
Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antip
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