PeptideDB

Fluplatin

CAS: F: C48H56F2N4O8Pt W: 1050.06

Fluplatin is a prodrug composed of cisplatin and fluvastatin. Fluplatin has antitumor activity.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Fluplatin is a prodrug composed of cisplatin and fluvastatin. Fluplatin has antitumor activity[1].
Invitro Fluplatin 对 H1975、A549 和 A549/DDP 细胞的 IC50 值分别为 2.24、4.57 和 4.51 μM。[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Fluplatin 相关抗体:
In Vivo Fluplatin (10.49 mg/kg, 尾静脉注射, 三天一次,共 5 次) 在 H1975 细胞皮下肿瘤模型中表现出更好的抑瘤活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
Formula C48H56F2N4O8Pt
Molar Mass 1050.06
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Bi YY, et al. Nanoparticles targeting mutant p53 overcome chemoresistance and tumor recurrence in non-small cell lung cancer. Nat Commun. 2024 Mar 29;15(1):2759.