Bioactivity | Fluplatin is a prodrug composed of cisplatin and fluvastatin. Fluplatin has antitumor activity[1]. |
Invitro | Fluplatin 对 H1975、A549 和 A549/DDP 细胞的 IC50 值分别为 2.24、4.57 和 4.51 μM。[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Fluplatin 相关抗体: |
In Vivo | Fluplatin (10.49 mg/kg, 尾静脉注射, 三天一次,共 5 次) 在 H1975 细胞皮下肿瘤模型中表现出更好的抑瘤活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
Formula | C48H56F2N4O8Pt |
Molar Mass | 1050.06 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bi YY, et al. Nanoparticles targeting mutant p53 overcome chemoresistance and tumor recurrence in non-small cell lung cancer. Nat Commun. 2024 Mar 29;15(1):2759. |