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Fluphenazine enanthate

CAS: 2746-81-8 F: C29H38F3N3O2S W: 549.69

Fluphenazine enanthate is the first long-acting injectable (LAI) antipsychotic for the treatment of schizophrenia.
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Bioactivity Fluphenazine enanthate is the first long-acting injectable (LAI) antipsychotic for the treatment of schizophrenia[1][2].
In Vivo Fluphenazine enanthate (2,4, 8 mg/kg; IM) significant inhibition of the avoidance performance is observed as long as 16, 23, and 28 days, respectively[1].Fluphenazine enanthate (8 mg/kg) drinking behavior is almost completely suppressed for 24 hours immediately following the administration[1].Fluphenazine enanthate (8 mg/kg) produces transient body weight Iosses in the rats[1]. Animal Model:
Name Fluphenazine enanthate
CAS 2746-81-8
Formula C29H38F3N3O2S
Molar Mass 549.69
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kuribara H, et al. Effects of fluphenazine enanthate and fluphenazine decanoate on discriminated avoidanceresponse and water drinking behavior in rats. Psychopharmacology (Berl). 1979 Sep;65(1):1-6. [2]. Brissos S, et al. The role of long-acting injectable antipsychotics in schizophrenia: a critical appraisal. Ther Adv Psychopharmacol. 2014 Oct;4(5):198-219.