Bioactivity | Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy[1]. |
Name | Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone |
CAS | 1926163-65-6 |
Sequence | {Fluorescein-6-carbonyl}-{Asp(OMe)}-{Glu(OMe)}-Val-{dl-Asp(OMe)}-{Fluoromethylketone} |
Shortening | {Fluorescein-6-carbonyl}-{Asp(OMe)}-{Glu(OMe)}-V-{dl-Asp(OMe)}-{Fluoromethylketone} |
Formula | C43H45FN4O16 |
Molar Mass | 892.83 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. M Kalai, et al. Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA. Cell Death Differ. 2002 Sep;9(9):981-94. |