Bioactivity | Fluorapacin is an anti-tumor agent. A stability-indicating HPLC method was developed for its quantitative determination in pharmaceuticals, utilizing a Spherisorb ODS II C18 column with acetonitrile/water as the mobile phase. Analysis was performed at 40°C with a 1.0 mL/min flow rate and UV detection at 218 nm. The method demonstrated a linear calibration curve (160–240 μg/mL, R2=0.9997), LOD of 1.4 ng/mL, and LOQ of 7.0 ng/mL. The method showed high accuracy, precision (R.S.D. <1.0%), and recovery rates (98.27% and 100.40%), making it reliable for quality control of fluorapacin API and drug products[1]. |
CAS | 869811-23-4 |
Formula | C14H12F2S3 |
Molar Mass | 314.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |