| Bioactivity | Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1]. | |||||||||
| Name | Fluoflavine | |||||||||
| CAS | 531-46-4 | |||||||||
| Formula | C14H10N4 | |||||||||
| Molar Mass | 234.26 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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| Reference | [1]. SJ Brown, et al. Probe Report for NOX1 Inhibitors. |