| Bioactivity | Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes[1][2][3][4]. | ||||||||||||
| Invitro | Fludarabine (5 μM; 48 hours) induces a decrease in p27kip1 expression[4]. Western Blot Analysis[4] Cell Line: | ||||||||||||
| Name | Fludarabine | ||||||||||||
| CAS | 21679-14-1 | ||||||||||||
| Formula | C10H12FN5O4 | ||||||||||||
| Molar Mass | 285.23 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Fludarabine
CAS: 21679-14-1 F: C10H12FN5O4 W: 285.23
Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in
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