| Bioactivity | FL3 is a flavagline with potent and selective cytotoxicity in cancer cells. FL3 induces apoptosis of HL60 and Hela cells by triggering the translocation of Apoptosis Inducing Factor (AIF) and caspase-12 to the nucleus[1]. |
| CAS | 1186012-80-5 |
| Formula | C25H23BrO5 |
| Molar Mass | 483.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Frédéric Thuaud, et al. Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. J Med Chem. 2009 Aug 27;52(16):5176-87. |
Flavagline FL3
CAS: 1186012-80-5 F: C25H23BrO5 W: 483.35
FL3 is a flavagline with potent and selective cytotoxicity in cancer cells. FL3 induces apoptosis of HL60 and Hela cells
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