| Bioactivity | Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome[1][2]. |
| Name | Flaccidoside II |
| CAS | 140694-19-5 |
| Formula | C59H96O25 |
| Molar Mass | 1205.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang GB, et al. Corrigendum to "Flaccidoside II ameliorates collagen-induced arthritis in mice" [Eur. J. Pharmacol. 880 (2020) 173155]. Eur J Pharmacol. 2021 Apr 15;897:173963. [2]. Han LT, et al. Triterpenoid saponin flaccidoside II from Anemone flaccida triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors via the MAPK-HO-1 pathway. Onco Targets Ther. 2016 Apr 5;9:1969-79. |
Flaccidoside II
CAS: 140694-19-5 F: C59H96O25 W: 1205.38
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell l
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