| Bioactivity | Fitusiran sodium, an small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. Fitusiran sodium increases thrombin generation and has the potential for the research of the hemophilia[1]. |
| Formula | C520H635F21N175Na44O309P43S6 |
| Molar Mass | 17215.34 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Pasi KJ, et al. Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort. J Thromb Haemost. 2021;19(6):1436-1446. |
Fitusiran sodium
CAS: F: C520H635F21N175Na44O309P43S6 W: 17215.34
Fitusiran sodium, an small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower productio
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