| Bioactivity | Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases[1]. |
| Invitro | Fingolimod phosphate 可防止淋巴细胞移出淋巴器官并抑制自身反应性淋巴细胞浸润中枢神经系统[1]。Fingolimod phosphate（0、1、10、100 nM）结合 S1P1 受体，下调激活的小胶质细胞产生促炎细胞因子，如肿瘤坏死因子-a、白介素-1β 和白介素-6[1].Fingolimod phosphate（0、1、10、100 nM）也上调小胶质细胞产生脑源性神经营养因子和胶质细胞源性神经营养因子[1]。 |
| Name | Fingolimod phosphate |
| CAS | 402615-91-2 |
| Formula | C19H34NO5P |
| Molar Mass | 387.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hiromi Noda, et al. Fingolimod phosphate promotes the neuroprotective effects of microglia. J Neuroimmunol. 2013 Mar 15;256(1-2):13-8. |
Fingolimod phosphate
CAS: 402615-91-2 F: C19H34NO5P W: 387.45
Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod p
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