Bioactivity | Filipin complex is a potent broad spectrum 28-membered ring pentaene macrolide antifungal antibiotic. Filipin complex is also a highly fluorescent polyene. Filipin complex specifically binds free cholesterol and is well established as a histochemical marker for the detection of unesterified cellular cholesterol. Filipin complex consists of four analogues (Filipins I-IV), with Filipin III (HY-N6718) comprising the bulk (>70%) of the complex[1][2][3]. | |||||||||
Invitro | Filipin complex interacts with membrane sterols causing the alteration of membrane structure[2]. For cholesterol staining, cells were incubated with Filipin complex for 2 h[3]. | |||||||||
Name | Filipin complex | |||||||||
CAS | 11078-21-0 | |||||||||
Formula | C35H58O11 (for Filipin III) | |||||||||
Molar Mass | 654.80 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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