| Bioactivity | Filipin II is an antibiotic, which exhibits antifungal efficacy. Filipin II interacts with membrane sterols, leads to changes in membrane structure, inhibits Candida utilis and Saccharomyces cerevisiae with the MIC of 0.03 mg/L and 0.2 μg/L[1][2]. |
| CAS | 38620-77-8 |
| Formula | C35H58O10 |
| Molar Mass | 638.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Payero TD, et al., Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives. Microb Cell Fact. 2015 Aug 7;14:114. [2]. Gao H, et al. Filipins: the first antifungal “weed killers” identified from bacteria isolated from the trap-ant[J]. Rsc Advances, 2014, 4(100): 57267-57270. |