PeptideDB

Fidaxomicin

CAS: 873857-62-6 F: C52H74Cl2O18 W: 1058.04

Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research[1][2][3].
Invitro Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora[1].Fidaxomicin is not inhibitory to commonly cultured bowel commensals (MIC90 >1024 μg/mL)[2].
Name Fidaxomicin
CAS 873857-62-6
Formula C52H74Cl2O18
Molar Mass 1058.04
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month