Bioactivity | Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research[1][2][3]. | ||||||||||||
Invitro | Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora[1].Fidaxomicin is not inhibitory to commonly cultured bowel commensals (MIC90 >1024 μg/mL)[2]. | ||||||||||||
Name | Fidaxomicin | ||||||||||||
CAS | 873857-62-6 | ||||||||||||
Formula | C52H74Cl2O18 | ||||||||||||
Molar Mass | 1058.04 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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