Bioactivity | Ferroptosis-IN-7(Compound 26) is a ferroptosis inhibitor which can restore cell viability, reduce iron accumulation and scavenge reactive oxygen species. Ferroptosis-IN-7 can be used for vascular diseases research[1]. |
Invitro | Ferroptosis-IN-7 (10 μM, 24 h) 可在 10 μM Erastin (HY-15763) 共处理下恢复细胞活力,减少铁和 ROS 积累,维持线粒体膜电位,增加 GSH 水平,降低 LPO 和 MDA 含量,上调 GPX4 表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Ferroptosis-IN-7 相关抗体: |
Formula | C32H40N4O3S |
Molar Mass | 560.75 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ji HL, et al. Design, synthesis, and evaluation of formylpiperazine analogs of Ferrostatin-1 as novel improved ferroptosis inhibitors. Bioorg Med Chem. 2024 Apr 9;105:117716. |