| Bioactivity | Ferroptosis-IN-15 (compound 12) is a potent inhibitor of ferroptosis, with the EC50s of 0.76 and 0.67 μM in A375 cells and 786-O cells, respectively.Ferroptosis-IN-15 is a potential iron chelator and radical trapping antioxidant[1]. |
| CAS | 1260669-24-6 |
| Formula | C17H14O5 |
| Molar Mass | 298.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zheng-Biao Zou, et al. Nigenolides A–H, 13 new microperfuranones with ferroptosis inhibitory activity from the deep-sea-derived Aspergillus niger. Bioorganic Chemistry Volume 153, December 2024, 107919 |
Ferroptosis-IN-15
CAS: 1260669-24-6 F: C17H14O5 W: 298.29
Ferroptosis-IN-15 (compound 12) is a potent inhibitor of ferroptosis, with the EC50s of 0.76 and 0.67 μM in A375 cells
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