| Bioactivity | Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1]. | ||||||||||||
| Invitro | Fenvalerate is inactive for PP2B-Bβ[1]. | ||||||||||||
| Name | Fenvalerate | ||||||||||||
| CAS | 51630-58-1 | ||||||||||||
| Formula | C25H22ClNO3 | ||||||||||||
| Molar Mass | 419.90 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. E Enan, et al. Specific Inhibition of Calcineurin by Type II Synthetic Pyrethroid Insecticides. Biochem Pharmacol. 1992 Apr 15;43(8):1777-84. [2]. A R Reilein, et al. Regulation of Organelle Movement in Melanophores by Protein Kinase A (PKA), Protein Kinase C (PKC), and Protein Phosphatase 2A (PP2A). J Cell Biol. 1998 Aug 10;142(3):803-13. |
Fenvalerate
CAS: 51630-58-1 F: C25H22ClNO3 W: 419.90
Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate
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