| Bioactivity | Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID). Fenoprofen can be used to to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Fenoprofen is an allosteric enhancer for melanocortin receptors. Fenoprofen also increases ERK1/2 activation[1][2]. | ||||||||||||
| Name | Fenoprofen | ||||||||||||
| CAS | 29679-58-1 | ||||||||||||
| Formula | C15H14O3 | ||||||||||||
| Molar Mass | 242.27 | ||||||||||||
| Appearance | Viscous liquid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Tahereh Rezaei, et al. A universal methodology for reliable predicting the non-steroidal anti-inflammatory drug solubility in supercritical carbon dioxide. Sci Rep. 2022 Jan 20;12(1):1043. [2]. Xiao-Chen Yuan, et al. Fenoprofen-An Old Drug Rediscovered as a Biased Allosteric Enhancer for Melanocortin Receptors. ACS Chem Neurosci. 2019 Mar 20;10(3):1066-1074. |