| Bioactivity | Fenoldopam mesylate (SKF-82526) is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis[1][2][3]. |
| Invitro | Fenoldopam is a partial agonist with low efficacy at DA1 receptors linked to cAMP generation in the LLC-PK1 cells[1].Fenoldopam (0-300 μM; 48 or 72 h) displays significant antiproliferative activity against RCC cell lines[2].Fenoldopam (5 μM and 10 μM; 72 h) induces cell apoptosis in a dose-dependent manner[2]. Cell Proliferation Assay[1] Cell Line: |
| Name | Fenoldopam mesylate |
| CAS | 67227-57-0 |
| Formula | C17H20ClNO6S |
| Molar Mass | 401.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Fenoldopam mesylate
CAS: 67227-57-0 F: C17H20ClNO6S W: 401.86
Fenoldopam mesylate (SKF-82526) is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC5
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