| Bioactivity | Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus)[1]. |
| Name | Feglymycin |
| CAS | 209335-49-9 |
| Sequence | {d-nTyr}-{d-Phg(3,5-OH)}-Val-{d-Phg(3,5-OH)}-{nTyr}-{d-Phg(3,5-OH)}-{nTyr}-{d-Phg(3,5-OH)}-Val-{d-Phg(3,5-OH)}-{nTyr}-Phe-Asp |
| Shortening | {d-nTyr}-{d-Phg(3,5-OH)}-V-{d-Phg(3,5-OH)}-{nTyr}-{d-Phg(3,5-OH)}-{nTyr}-{d-Phg(3,5-OH)}-V-{d-Phg(3,5-OH)}-{nTyr}-FD |
| Formula | C95H97N13O30 |
| Molar Mass | 1900.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Vértesy L, et al. Feglymycin, a novel inhibitor of the replication of the human immunodeficiency virus. Fermentation, isolation and structure elucidation. J Antibiot (Tokyo). 1999 Apr;52(4):374-82. [2]. Dettner F, et al. Total synthesis of the antiviral peptide antibiotic feglymycin. Angew Chem Int Ed Engl. 2009;48(10):1856-61. |
Feglymycin
CAS: 209335-49-9 F: C95H97N13O30 W: 1900.86
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC
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