| Bioactivity | Fascaplysin is an antimicrobial and cytotoxic red pigment, that can come from the marine sponge (Fascaplysinopsis sp.). Fascaplysin has been synthesized in seven steps from indole (65% yield). Fascaplysin can induces apoptosis and autophagy in human leukemia HL-60 cells. Fascaplysin shows anti-tumor activity[1][2]. |
| Invitro | Fascaplysin induces autophagy as a cytoprotective response via ROS and p8 in vascular endothelial cells (VECs)[2].Fascaplysin targets metabolic activity of the prostate cancer cells, without disrupting cell membrane's integrity[2]..Fascaplysin induces caspase mediated crosstalk between apoptosis and autophagy through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells[2]. |
| Name | Fascaplysin |
| CAS | 114719-57-2 |
| Formula | C18H11ClN2O |
| Molar Mass | 306.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Fascaplysin
CAS: 114719-57-2 F: C18H11ClN2O W: 306.75
Fascaplysin is an antimicrobial and cytotoxic red pigment, that can come from the marine sponge (Fascaplysinopsis sp.).
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